2009 Summer Project Week 4D Imaging

Home < 2009 Summer Project Week 4D Imaging

Key Investigators

Implement a set of 3D Slicer modules to handle 4D images in 3D Slicer for perfusion analysis, cardiac, etc. including:

Manipulation
- Loading 4D volume
- Scroll time-line
- 4D image editing
- Recording 4D Gated US
Processing
- Image registration for motion compensation
Analysis
- Perfusion analysis: fitting pharmacokinetic model

We will work on the following tasks:

Implementation of 4D Image module that provides:
- 4D image loading: Loading a series of 3D images from a specified director. The data can be either in DICOM or NRRD format.
- Time line scroll-bar interface: scrolling the frame in time-direction. It allows you to scroll the frame for foreground and background screens independently to compare two images at the different time points.
- Frame editing: Reorganizing the time series data (optional)
Implementation of 4D Analysis module that provides:
- Intensity plot: Plotting temporal changes of intensities at specified regions. This feature is useful for analyzing dynamic contrast images.
- Model fitting: A python interface to analyze intensity curves obtained from the 4D images. The interface is useful to fit pharmacokinetic models to intensity curves to obtain perfusion parameters.
Investigating BatchMake as an infrastructure for time-series image processing.
- 4D Cropping: Cropping volumes in a time-series data using BatchMake.
- 4D Image registration: Registering each volume frame to a key-frame to compensate organ motion.
- Image registration using cluster (Optional)

Before the project week, we have completed:

Initial implementation of 4D Image module. The module is available at http://svn.slicer.org/Slicer3/trunk/Modules/FourDImage
Initial implementation of 4D Analysis module. The Python interface has to be fixed. The module is available at http://svn.slicer.org/Slicer3/trunk/Modules/FourDAnalysis

The preliminary module implementation is described in Slicer3:FourDAnalysis.