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Introduction

History: During MICCAI we (Ron Kikinis, Guido Gerig, Ross Whitaker, Polina Golland, Jim Miller, Tina Kapur, Martin Styner) discussed plans for the current year of NA-MIC. Given that this is the last year for the current participants in Core 3, we need to plan specific activities.
We will have an information exchange between Core 1 and Core 3 to discuss
- a) clinical hypothesis and image analysis questions,
- b) refined existing and new data sets related to a) and
- c) refined and new algorithms available and ready to meet requirements of a) and b). Emphasis will be on the question what actions to take that will result in NA-MIC clinical application science papers especially w.r.t. the "low hanging fruits" discussed at the AHM.

Logistics

The venue is the conference room on the second floor of our 1249 Boylston Street Facility (directions) in Boston on October 17 between 9.30am and 3pm.
Nancy Maxwell will be waiting downstairs to let you in the building. Call her at 617 525 6105 if she is not there.

Intro: Ron
Core 3: Discussion of newly available data (moderated by Martha Shenton & Andy Saykin)
1. New Core 3 Data
Core 1: Discussion of algorithms and processing capabilities that candidates in this effort (moderated by Ross Whitaker & Guido Gerig).

Identify specific analyses that should be initiated now. Specify teams, interactions and timetables (moderated by Ron Kikinis).
03.00pm Adjourn

UF: 2 ROI tractography analysis with mean FA measures, doDTI ... submitted to Brain.
CF: previously defined ROIs, tractography with behavioral Stroop data, doDTI ... submitted to Archives of General Psychiatry.
AF: Registration of Susumu Mori’s atlas to our cases. Slicer Nonlinear FA to FA. No results. Need better registration.
CC: (1) Tractography. Fibers seeded in one slice CC ROI. Automated fiber clustering results in ROI color coded based on fiber clustering (Slicer, MIT Collaboration).

(2) Atlas based approach warping a CC subdivision to individual cases (UNC Collaboration).

ALIC: Work in progress. Tractography from anterior and posterior limb of the internal capsule. Slicer
STG: Mean FA, mean diffusivity within ROI defined on SPGR Slicer ... submitted to Biological Psychiatry.

Registration:
- Inter-subject diffusion to diffusion registration.
- Intra- and inter-subject co-registration of structural, diffusion and functional MRI.
DWI/tensor/fiber smoothing.
Fiber asymmetry computation.
Fiber registration.
Tractography of white matter structures seeded in gray matter areas.
3T artifact removal.
Segmentation of temporal lobe and basal ganglia.
Anatomical atlas for white and gray matter.