DBP:Harvard:Software:Minutes:4-26-06

DTI Meeting Minutes | April 26, 2006

Present: Doug, Marc, Katharina, Sylvain, Kang Uk, Gordon, CF, Marek, Gudrun

• Slicer
  • Slicer26 should be able to read NRRD DWIs now
  • doDTI gives you mean FA, would be nice to display this in Slicer somewhere

• New protocol: scanning today?
  • required that a licensed MD approve every scan
  • sequence will be DICOM files, probably same format as before, same procedure for downloading
  • Marek meeting with Nan-Quei at 1:30 today at the SPL to talk about the protocol
  • Will try multiple scans varying b-value and number of directions
    • Will try 750 and 1000 with minimum of 32 directions; also try 50 directions

• Anterior Commissure
  • would be nice to have an extra scalar map with orientation overlayed with the output of this method
  • Gordon will finish creating these maps and send to Sylvain

• Cingulum Bundle histograms of FA/Mode
  • note that people tend to overestimate how linear the ROI will be.. mostly orthotropic
  • now that we know that anisotropy is a bi-variate quantity, still need to answer the question about how to do statistics on this; non-parametric tests?
  • would be helpful to have comparison of different white matter ROIs, plotted in this space
    • Corpus callosum, cingulum bundle, STG white matter, STG gray matter, CSF; these ROIs will be sent to Gordon

• Kang Uk - problem with tensor coregistration?
  • script was updated by Mattan in slicer-nightly, but still doesn't seem to be working
  • will try a basic co-registration of two tensor sets in the same direction