2010 Summer Project Week Cortical Thickness Analysis

• 

  Projects List

• 

  ARCTIC: Automatic Regional Cortical ThICkness

• 

  GAMBIT: Group-wise Automatic Mesh-Based analysis of cortIcal Thickness

• 

  Cortical thickness on white matter surface

• 

  Sucal depth on genus-zero cortical surface

• 

  Particles on inflated genus-zero cortical surface

Key Investigators

• UNC: Yundi Shi, Martin Styner
• Emory: Mar Sanchez

Objective

To build an open-source software (mainly involving Slicer3) based pipeline for primate imaging, including skull stripping of T1,T2 and DTI images, tissue segmentation, cortical thickness analysis, atlas building and fiber tracing and tract-based analysis. This is part of a longitudinal study of rhesus macaque monkeys

Approach, Plan

Progress

Delivery Mechanism

This work will be delivered to the NA-MIC Kit as a:

1. ITK Module
2. Slicer Module
   1. Built-in
   2. Extension -- commandline - YES
   3. Extension -- loadable
3. Other (Please specify)

References

• I. Oguz, M. Niethammer, J. Cates, R. Whitaker, T. Fletcher, C. Vachet, and M. Styner, Cortical Correspondence with Probabilistic Fiber Connectivity, Information Processing in Medical Imaging, IPMI 2009, LNCS, in print.
• H.C. Hazlett, C. Vachet, C. Mathieu, M. Styner, J. Piven, Use of the Slicer3 Toolkit to Produce Regional Cortical Thickness Measurement of Pediatric MRI Data, presented at the 8th Annual International Meeting for Autism Research (IMFAR) Chicago, IL 2009.
• C. Vachet, H.C. Hazlett, M. Niethammer, I. Oguz, J.Cates, R. Whitaker, J. Piven, M. Styner, Mesh-based Local Cortical Thickness Framework, UNC Radiology Research Day 2010 abstract
• C. Mathieu, C. Vachet, H.C. Hazlett, G. Geric, J. Piven, and M. Styner, ARCTIC – Automatic Regional Cortical ThICkness Tool, UNC Radiology Research Day 2009 abstract