2015 Summer Project Week:T1 mapping

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  Projects List

Key Investigators

• Xiao Da (MGH), Yangming Ou (MGH), Andriy Fedorov (BWH), Jayashree Kalpathy-Cramer (MGH)
• Utsav (Observing)

Project Description

T1 mapping estimates effective tissue parameter maps (T1) from multi-spectral FLASH MRI scans with different flip angles. T1 mapping can be used to optimize parameters for a sequence, monitor diseased tissue, measure Ktrans in DCE-MRI and etc.

Objective

• Estimate effective T1 from multi-spectral FLASH MRI scans with different flip angles
• Implement T1 mapping algorithm as a Slicer extension using C++

Approach, Plan

• Start with prostate diffusion module
• Update equations for T1 mapping
• Compare the results using C++, Python, Freesurfer with ground truth of T1 for QIBA phantom
• Test the Slicer module on MGH Brain Tumor MR Data with multiple flip angles

Progress

• Equations have already been updated
• Working on the GUI
• Working on the comparison

References

• QIBA T1 phantom
• Basic equations for T1 mapping