2015 BRAINSFit registration in SimpleITK

Case 25

High irregulations in ITKv4

Resolved Irregulations ins ITKv4

Key Investigators

• Peter Behringer
• Andriy Fedorov
• Dženan Zukić

Project Description

Objective

• Our registration module for b-spline deformable registration of prostate MRI uses BRAINSFit in Slicer4/ITKv4.
• One issue that we are getting with Slicer4/ITKv4 is that they are a lot more irregular and unrealistic than what we used to get in Slicer3/ITKv3 (see summary here)
• The Slicer4/ITKv4 registration tool should be comparable with the functionality we had in Slicer3/ITKv3, which was evaluated here

Approach, Plan

• Implement a subset of BRAINSFit functionality used for supporting in-bore MRI-guided prostate biopsy in SimpleITK
• Get ideas from the community how the irregularity can be avoided and implemented in SimpleITK

Progress

• Initialization and rigid registration is implemented using SimpleITK
• We tracked the issue down using various parameters
• We used strongly dilated masks for the BSpline registration and results are looking much better