Difference between revisions of "2009 Summer Project Week Multimodal SPL Brain Atlas"

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__NOTOC__
 
__NOTOC__
 
<gallery>
 
<gallery>
Image:Thalamus.png
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Image:PW2009-v3.png|[[2009_Summer_Project_Week#Projects|Projects List]]
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Image:Thalamus.png|Thalamus
 
</gallery>
 
</gallery>
  
 
==Key Investigators==
 
==Key Investigators==
* BWH: Ion-Florin Talos
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* BWH: Ion-Florin Talos, Michael Halle, Wendy Plesniak
* Utah:
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* GE: Jim Miller
* UNC:
 
* Georgia Tech:
 
  
 
<div style="margin: 20px;">
 
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<h3>Objective</h3>
 
<h3>Objective</h3>
To create a segmentation pipeline for thalamic nuclei
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To explore ways of linking the image data of the SPL multi-modal brain atlas (label maps, 3D-models) with ontological information on brain morphology and function
  
  
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<h3>Approach, Plan</h3>
 
<h3>Approach, Plan</h3>
apply the spectral clustering approach to delineating the major thalamic nuclei in a high-resolution, volumetric DTI-dataset (voxel size 1 mm, 120 gradients)
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* continue work on XML-based intermediate data representation that supports anatomical hierarchies and can describe arbitrary overlapping image regions
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* application integration of the new XML-based data representation (3D-Slicer)
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* discussion of automated testing for atlas segmentation
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* discussion of integration of FMA with atlas
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</div>
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<div style="width: 40%; float: left;">
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<h3>Progress</h3>
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* met with interested users from the larger community to discuss project concepts and possible use cases
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* discussed collaboraton opportunities
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* will have followup engineering meeting with GE next week
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</div>
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</div>
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<div style="width: 97%; float: left;">
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==References==
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1. Talos IF, Rubin DL, Halle M, Musen MA, Kikinis R. A prototype symbolic model of canonical functional neuroanatomy of the motor system. J Biomed Inform. 2008 Apr;41(2):251-263.
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2. Rubin DL, Talos IF, Halle M, Musen MA, Kikinis R. Computational neuroanatomy: ontology-based representation of neural components and connectivity. BMC Bioinformatics 2009; 10(Suppl 2):S3.
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</div>

Latest revision as of 12:57, 26 June 2009

Home < 2009 Summer Project Week Multimodal SPL Brain Atlas

Key Investigators

  • BWH: Ion-Florin Talos, Michael Halle, Wendy Plesniak
  • GE: Jim Miller

Objective

To explore ways of linking the image data of the SPL multi-modal brain atlas (label maps, 3D-models) with ontological information on brain morphology and function


Approach, Plan

  • continue work on XML-based intermediate data representation that supports anatomical hierarchies and can describe arbitrary overlapping image regions
  • application integration of the new XML-based data representation (3D-Slicer)
  • discussion of automated testing for atlas segmentation
  • discussion of integration of FMA with atlas

Progress

  • met with interested users from the larger community to discuss project concepts and possible use cases
  • discussed collaboraton opportunities
  • will have followup engineering meeting with GE next week

References

1. Talos IF, Rubin DL, Halle M, Musen MA, Kikinis R. A prototype symbolic model of canonical functional neuroanatomy of the motor system. J Biomed Inform. 2008 Apr;41(2):251-263.

2. Rubin DL, Talos IF, Halle M, Musen MA, Kikinis R. Computational neuroanatomy: ontology-based representation of neural components and connectivity. BMC Bioinformatics 2009; 10(Suppl 2):S3.