Difference between revisions of "2010 Summer Project Week Quantification Of Lesion Diffusion Disruption"

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Image:PW-MIT2010.png|[[2010_Summer_Project_Week#Projects|Projects List]]
 
Image:PW-MIT2010.png|[[2010_Summer_Project_Week#Projects|Projects List]]
Image:genuFAp.jpg|Scatter plot of the original FA data through the genu of the corpus callosum of a normal brain.
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Image:TractsLesionZoomOverlay.png|Tracts interrupted by lesions with FA values.
Image:genuFA.jpg|Regression of FA data; solid line represents the mean and dotted lines the standard deviation.
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Image:Fa_dists.png|FA distributions for voxels near or inside lesions.
 
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<h3>Approach, Plan</h3>
 
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Our initial approach for quantifying diffusion interruption is to compile statistics on the distributions of FA at varying distances from lesion tissue.  Assuming there are significant differences more advanced methods, such as using graph laplacians to estimate probable tracts will be investigated.
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Our initial approach for quantifying diffusion interruption is to compile statistics on the distributions of FA at varying distances from lesion tissue.  Assuming there are significant differences more advanced methods will be investigated.
  
 
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<h3>Progress</h3>
 
<h3>Progress</h3>
Using diffusion tools in slicer FA images were created in the same space as the lesion images.  ITK code for summarizing statistics is almost complete.
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Using diffusion tools in slicer FA images were created in the same space as the lesion images.  ITK code for summarizing statistics is complete and analysis of all lupus subjects is under way.
  
 
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Latest revision as of 14:05, 25 June 2010

Home < 2010 Summer Project Week Quantification Of Lesion Diffusion Disruption


Key Investigators

  • ABMIG: H. J. Bockholt
  • MRN: Mark Scully

Objective

Quantify the effect lesions have on diffusion.



Approach, Plan

Our initial approach for quantifying diffusion interruption is to compile statistics on the distributions of FA at varying distances from lesion tissue. Assuming there are significant differences more advanced methods will be investigated.

Progress

Using diffusion tools in slicer FA images were created in the same space as the lesion images. ITK code for summarizing statistics is complete and analysis of all lupus subjects is under way.

Delivery Mechanism

This work will be delivered to the NA-MIC Kit as a Slicer3 commandline extension.