2012 Winter Project Week:hybridMRS

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Project Title: Generation of a hybrid MR-Spectroscopic (MRS) dataset under 3DSlicer

Key Investigators

  • SPL: Jan Egger, Isaiah Norton, Tina Kapur, Alexandra Golby
  • UKGM: Daniel Hořínek, Jens Sommer, Christopher Nimsky
  • ETHZ: Bjoern Menze
  • IKEM: Antonín Škoch

Objective

Generating a hybrid MR-Spectroscopic (MRS) dataset under 3DSlicer that can be used for fusion with the anatomic dataset under iPlan of BrainLAB in AMIGO. A hybrid MR-Spectroscopic dataset can for example be used for biopsy targeting in brain tumors.

Approach, Plan

Try to process MRS data with the MRSI module from Bjoern Menze developed at a previous project week. The module interfaces SIVIC, which is an open-source standards-based software framework and application suite for processing and visualization of DICOM MR Spectroscopy data.

Progress

-

Delivery Mechanism

Towards a 3DSlicer module...

Bibliography

Preoperative Grading of Gliomas by Using Metabolite Quantification with High-Spatial-Resolution Proton MR Spectroscopic Imaging. Radiology 2006 Mar;238(3):958-69.

Imaging of brain tumors: MR spectroscopy and metabolic imaging. Neuroimaging Clin N Am. 2010 Aug;20(3):293-310.

Use of in vivo two-dimensional MR spectroscopy to compare the biochemistry of the human brain to that of glioblastoma. Radiology. 2011 May;259(2):540-9. Epub 2011 Feb 25.

Resources

Sivic Sivic plugin for Slicer 3.?

http://www.brighamandwomens.org/Departments_and_Services/radiology/Research/Spectroscopy/Default.aspx

https://scion.duhs.duke.edu/svn/sample_data/siemens_rda_export/read_rda102.m

http://www.acrin.org/portals/0/protocols/6677/imaging/6677spectro_files_siemens.pdf

http://hci.iwr.uni-heidelberg.de/MIP/Software/csitools.php

http://tarquin.sourceforge.net/

jSIPRO - MR Spectroscopic Imaging Processing Tool