NA-MIC NCBC Collaboration:Automated FE Mesh Development

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Visualization of mesh quality

Abstract

Musculoskeletal finite element (FE) analysis is an invaluable tool in orthopedic-related research. While it has provided significant biomechanical insight, the demands associated with modeling the geometrically complex structures of the human body often limit its utility. The often-prohibitive amount of model development time is further compounded by the time required to process medical image datasets to identify the distinct anatomical structures of interest. Yet this process is a necessary preprocessing step for model development. As a result, most of the analyses reported in the literature refer to 'average' bone geometry. The broad objective of our research plan is to integrate and expand methods to automate the development of specimen- / patient-specific finite element (FE) models into the NA-MIC toolkit. In pursuit of this objective we propose to merge unique technologies to automate image dataset segmentation; material property extraction and assignment; and direct FE model development (automated meshing). While direct physical scans of the bones of interest will be used to validate the automated image segmentation routines, experimental cadaveric contact stress measurements will provide a standard against which to validate the FE contact formulations. Furthermore, the FE models generated by our software package will be compared to models of the same bone(s) created via a commercial pre-processing package. While the bones/joints of the upper extremity represent the primary structures of interest proposed in this application, the tools will be applicable to many orthopedic applications. In addition to expanding the NA-MIC toolkit beyond the brain, the proposed project will expand the image segmentation routines and finite element meshing routines currently available. This proposal will ultimately yield specimen-specific FE models of the various joints of the upper extremity. Such models will position us to provide information about the load transfer, characteristics of the normal joints and in the future to demonstrate, for example, the effects of ligamentous instabilities, posttraumatic misalignments, fractures, and various surgical procedures.

Grant#

R01EB005973

Key Personnel

Funding Duration

09/20/2006-06/30/2010

Projects

An initial version of the meshing tool was recently released as a standalone application called IA-FEMesh. This application is built completely on NA-MIC tools including ITK, VTK, and KWWidgets.


Active projects in this collaboration are:

Meshing Algorithms

  1. Voxel Meshing Module (Iowa)
  2. Novel Hexahedral Meshing Algorithms (Iowa)
  3. Mapped Hexahedral Meshing (Iowa)
  4. Hex vs Tet Mesh Comparisons (Iowa/Isomics/BWH)

Automated Segmentation

  1. EM Segmentation For Orthopaedic Applications (Iowa)
  2. Integration of Neural Network Algorithms (Iowa)

Image Registration

  1. Evaluation of Inter-Modality Registration (Iowa/Isomics)

Validation

  1. Validation of Defined Regions of Interest Using Surface Scanning (Iowa)
  2. FE Mesh Validation (Iowa)

Mesh Quality Visualization

  1. FE Mesh Quality Visualization (Iowa/Isomics)
  2. Standalone FE Mesh Quality Viewer
  3. Mesh Quality Command Line Module

Mesh Improvement

  1. Mesh Quality Improvement

Slicer3 Integration

  1. Slicer Interactive Module
  2. Mesh KWWidgets Interface
  3. Slicer3 Mesh Meeting October 2008

Slicer3 Meshing Tutorial

  1. Iowa Meshing Tutorial - Tutorial showing how to mesh the proximal phalanx bone with an example dataset

Publications

Meetings and Events Specific to this Collaboration

  • 2006
    • Vincent Magnotta presented background information about the data acquisitioin and validation at the 2006 NA-MIC AHM (Slides: Validation of Bone Models using 3D Surface Scanning).
    • Orthopaedic Research Society - 2006
      • Gassman, E.E., S.M. Powell, V.A. Magnotta, and N.M. Grosland. Automating the identification of bony structures using artificial neural networks. in 52nd Annual Meeting of the Orthopaedic Research Society. 2006. Chicago, IL.
    • MICCAI - 2006
      • Shivanna, K.H., B.D. Adams, V.A. Magnotta, and N.M. Grosland. Automating patient-specific finite element model development. in 9th MICCAI Conference. 2006. Copenhagen.
    • November 7-8, 2006: Meshing Collaborator Project Visit to BWH
  • 2007
    • NA-MIC All Hands Meeting Update 2007
    • American Society of Biomechanics 2007
      • Grosland, N.M., C. Lisle, K.H. Shivanna, S. Pieper, and V.A. Magnotta. A check of mesh quality. in American Society of Biomechanics. 2007. Palo Alto, CA. Nicole Grosland presents at the American Society of Biomechanics 2007, Palo Alto, CA
      • Tadepalli, S.C., K.H. Shivanna, V.A. Magnotta, and N.M. Grosland. Patient-specific orthopaedic surgical planning: Image data sets to FE models. in American Society of Biomechanics. 2007. Palo Alto, CA.
      • DeVries, N.A., E.E. Gassman, N.A. Kallemeyn, K.H. Shivanna, V.A. Magnotta, and N.M. Grosland. Validation of orthopaedic related image segmentation techniques. in American Society of Biomechanics. 2007. Palo Alto, CA.
      • Bafna, R., V.A. Magnotta, and N.M. Grosland. Automated hexahedral meshing of anatomical structures using deformable registration. in American Society of Biomechanics. 2007. Palo Alto, CA.
  • Orthopaedic Research Society - 2008
    • Ramme A, Magnotta V, Grosland NM. Comparison of the Expectation Maximization Algorithm and an Artificial Neural Network for Automated Bone Segmentation.
  • ASME Summer Bioengineering Conference - 2008 - Marco Island, FL.
    • Shivanna K, Kallemeyn N, Tadepalli S, DeVries N, Magnotta V, Grosland N. IA-FeMesh: An Interactive All Hexahedral Mesh Generator For Discrete Anatomic Closed Surfaces.
    • Tadepalli SC, Kallemeyn NA, Shivanna KH, Smucker J, Fredericks DC, Grosland NM. Cervical Laminoplasty Construct Stability: A Finite Element Study.
    • Kallemeyn NA, Tadepalli SC, Shivanna KH, Grosland NM. Toward Patient-Specific Cervical Spine Functional Spinal Unit FE Modeling and Validation.


  • Meshing Tcon September 26
  • Pre-ORS meeting - 2009
    • Tadepalli SC, Shivanna KH, Magnotta VA, Grosland NM. Patient –Specific Hexahedral Mesh Generation for Orthopaedic Surgical Planning.
  • Orthopaedic Research Society - 2009
  • ASME Summer Bioengineering Conference - 2009 - Lake Tahoe, CA
    • Tadepalli SC, Shivanna KH, Magnotta VA, Grosland NM. A Semi-Automated Hexahedral Mesh Generation of the Articular Cartilage.
    • Kiran H Shivanna, Srinivas C Tadepalli, Vincent A Magnotta, Nicole M Grosland, A Framework for Finite Element Mesh Quality Improvement and Visualization in Orthopaedic Biomechanics.
  • American Society of Biomechanics - 2009 - State College PA
    • Shivanna KH, Tadepalli SC, Magnotta VA, Grosland NM. Feature based all hexahedral mesh generation in orthopaedic applications

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