Difference between revisions of "Projects:DTINoiseStatistics"

From NAMIC Wiki
Jump to: navigation, search
 
(16 intermediate revisions by 2 users not shown)
Line 1: Line 1:
 +
Back to [[Algorithm:Utah2|Utah 2 Algorithms]]
 +
__NOTOC__
 
= DTI Noise Statistics =
 
= DTI Noise Statistics =
  
  Back to [[NA-MIC_Collaborations|NA-MIC_Collaborations]], [[Algorithm:UNC|UNC Algorithms]]
+
Clinical time limitations on the acquisition of diffusion weighted volumes in DTI present several key challenges for quantitative statistics of diffusion tensors and tensor-derived measures.  First, the signal to noise ratio (SNR) in each individual diffusion weighted volume is relatively low due to the need for quick acquisition.  Secondly, the presence of Rician noise in MR imaging can introduce bias in the estimation of anisotropy and trace. Unlike structural MRI where intensities are primarily used to obtain contrast, the goal of DTI is to quantify the local diffusion properties in each voxel.  Therefore, an understanding of the influence of imaging noise on the distribution of measured values is important to understand the results of statistical analysis and to design new imaging protocols.
 
 
'''Objective'''
 
  
Clinical time limitations on the acquisition of diffusion weighted volumes in DTI present several key challenges for quantitative statistics of diffusion tensors and tensor-derived measures.  First, the signal to noise ratio (SNR) in each individual diffusion weighted volume is relatively low due to the need for quick acquisition.  Secondly, the presence of Rician noise in MR imaging can introduce bias in the estimation of anisotropy and trace.  Unlike structural MRI where intensities are primarily used to obtain contrast, the goal of DTI is to quantify the local diffusion properties in each voxel.  Therefore, an understanding of the influence of imaging noise on the distribution of measured values is important to understand the results of statistical analysis and to design new imaging protocols.
+
= Key Investigators =
  
'''Progress'''
+
Utah: Casey Goodlett, Guido Gerig, Tom Fletcher, Ross Whitaker
  
''References''
+
= Publications =
  
'''Key Investigators'''
+
''In Print''
 +
* [http://www.na-mic.org/publications/pages/display?search=DTINoiseStatistics&submit=Search&words=all&title=checked&keywords=checked&authors=checked&abstract=checked&sponsors=checked&searchbytag=checked| NA-MIC Publications Database on Influence of Imaging Noise on DTI Statistics]
  
'''Links'''
 
  
 
  Project Week Results: [[Media:Riemannian_DTI_ProgWeek2006.ppt|Jan 2006]], [[Media:2006_Summer_Project_Week_DTI_Processing.ppt|Jun 2006]], [[Media:2007_Project_Half_Week_TensorEstimation.ppt|Jan 2007]]
 
  Project Week Results: [[Media:Riemannian_DTI_ProgWeek2006.ppt|Jan 2006]], [[Media:2006_Summer_Project_Week_DTI_Processing.ppt|Jun 2006]], [[Media:2007_Project_Half_Week_TensorEstimation.ppt|Jan 2007]]
 +
 +
[[Category: Statistics]] [[Category:Diffusion MRI]]

Latest revision as of 20:30, 11 May 2010

Home < Projects:DTINoiseStatistics
Back to Utah 2 Algorithms

DTI Noise Statistics

Clinical time limitations on the acquisition of diffusion weighted volumes in DTI present several key challenges for quantitative statistics of diffusion tensors and tensor-derived measures. First, the signal to noise ratio (SNR) in each individual diffusion weighted volume is relatively low due to the need for quick acquisition. Secondly, the presence of Rician noise in MR imaging can introduce bias in the estimation of anisotropy and trace. Unlike structural MRI where intensities are primarily used to obtain contrast, the goal of DTI is to quantify the local diffusion properties in each voxel. Therefore, an understanding of the influence of imaging noise on the distribution of measured values is important to understand the results of statistical analysis and to design new imaging protocols.

Key Investigators

Utah: Casey Goodlett, Guido Gerig, Tom Fletcher, Ross Whitaker

Publications

In Print


Project Week Results: Jan 2006, Jun 2006, Jan 2007