T1 mapping for variable flip angle

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Key Investigators

  • MGH: Xiao Da, Artem Mamonov, Jayashree Kalpathy-Cramer
  • BWH: Andriy Fedorov

Project Description

Objective

  • Estimate effective T1 from multi-spectral FLASH MRI scans with different flip angles

Approach, Plan

  • Create a Slicer module for T1 mapping for multiple flip angles using Python script
  • Run Python script and Freesurfer code on QIBA T1 phantom
  • Test the Slicer module on MGH Brain Tumor MR Data with multiple flip angles

Progress

  • Compared the results using Python with Freesurfer and ground truth of T1 for QIBA data
  • T1 mapping results on QIBA data using Slicer+Python are almost identical to the results using Freesurfer and comparable with the ground truth

References