Difference between revisions of "2010 NAMIC Project week:LongitudinalPETSUV Wizard"

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(Created page with '__NOTOC__ <gallery> Image:PW-MIT2010.png|Projects List Image:genuFAp.jpg|Scatter plot of the original FA data through the genu of the corpus…')
 
 
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__NOTOC__
 
__NOTOC__
 
<gallery>
 
<gallery>
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Image:PW-MIT2010.png|[[2010_Summer_Project_Week#Projects|Projects List]]
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Image:PET2010projectweek.png|PET
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Image:genuFAp.jpg|Scatter plot of the original FA data through the genu of the corpus callosum of a normal brain.
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Image:ROI2010projectweek.png|ROI
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Image:genuFA.jpg|Regression of FA data; solid line represents the mean and dotted lines the standard deviation.
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Image:SUV2010projectweek.png|SUV
 
</gallery>
 
</gallery>
  
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==Instructions for Use of this Template==
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[[2010_Summer_Project_Week#NA-MIC_Kit_Internals | Back to NA-MIC Kit Internals, Summer Project Week 2010]]
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#Please create a new wiki page with an appropriate title for your project using the convention Project/<Project Name>
 
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#Copy the entire text of this page into the page created above
 
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#Link the created page into the list of projects for the project event
 
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#Delete this section from the created page
 
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#Send an email to tkapur at bwh.harvard.edu if you are stuck
 
  
 
==Key Investigators==
 
==Key Investigators==
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* UNC: Isabelle Corouge, Casey Goodlett, Guido Gerig
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* BWH: Wendy Plesniak, Alex Zaitsev, Ron Kikinis
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* Utah: Tom Fletcher, Ross Whitaker
 
  
 
<div style="margin: 20px;">
 
<div style="margin: 20px;">
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<h3>Objective</h3>
 
<h3>Objective</h3>
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We are developing methods for analyzing diffusion tensor data along fiber tracts. The goal is to be able to make statistical group comparisons with fiber tracts as a common reference frame for comparison.
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We are developing a Slicer command-line module for PET SUV computation and a wizard interface to a specific workflow for PET SUV computation for longitudinal studies.  
  
  
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<h3>Approach, Plan</h3>
 
<h3>Approach, Plan</h3>
  
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Our approach for analyzing diffusion tensors is summarized in the IPMI 2007 reference below.  The main challenge to this approach is <foo>.
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Our approach will be very similar to the ChangeTracker wizard in Slicer3.
  
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Our plan for the project week is to first try out <bar>,...
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Our plan for the project week is to  
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* design the steps of the workflow
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* implement the GUI
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* implement the MRML nodes to hold state
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* discuss design of proper (CLI) interfaces to workflow engine
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* and begin to hook up logic, mrml and gui.
  
 
</div>
 
</div>
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<h3>Progress</h3>
 
<h3>Progress</h3>
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Software for the fiber tracking and statistical analysis along the tracts has been implemented. The statistical methods for diffusion tensors are implemented as ITK code as part of the [[NA-MIC/Projects/Diffusion_Image_Analysis/DTI_Software_and_Algorithm_Infrastructure|DTI Software Infrastructure]] project. The methods have been validated on a repeated scan of a healthy individual. This work has been published as a conference paper (MICCAI 2005) and a journal version (MEDIA 2006). Our recent IPMI 2007 paper includes a nonparametric regression method for analyzing data along a fiber tract.
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* Commandline Module for SUV computation with multiple VOIs, multiple timepoints started. Close to being finished and will provide a calling convention for Alex to use in his workflow engine.
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</div>
 
</div>
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==Delivery Mechanism==
 
==Delivery Mechanism==
  
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This work will be delivered to the NA-MIC Kit as a (please select the appropriate options by noting YES against them below)
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This work will be delivered to the NA-MIC Kit as a built-in module in Slicer3.7
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#ITK Module
 
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#Slicer Module
 
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##Built-in
 
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##Extension -- commandline
 
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##Extension -- loadable
 
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#Other (Please specify)
 
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==References==
 
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*Fletcher P, Tao R, Jeong W, Whitaker R. [http://www.na-mic.org/publications/item/view/634 A volumetric approach to quantifying region-to-region white matter connectivity in diffusion tensor MRI.] Inf Process Med Imaging. 2007;20:346-358. PMID: 17633712.
 
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* Corouge I, Fletcher P, Joshi S, Gouttard S, Gerig G. [http://www.na-mic.org/publications/item/view/292 Fiber tract-oriented statistics for quantitative diffusion tensor MRI analysis.] Med Image Anal. 2006 Oct;10(5):786-98. PMID: 16926104.
 
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* Corouge I, Fletcher P, Joshi S, Gilmore J, Gerig G. [http://www.na-mic.org/publications/item/view/1122 Fiber tract-oriented statistics for quantitative diffusion tensor MRI analysis.] Int Conf Med Image Comput Comput Assist Interv. 2005;8(Pt 1):131-9. PMID: 16685838.
 
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* Goodlett C, Corouge I, Jomier M, Gerig G, A Quantitative DTI Fiber Tract Analysis Suite, The Insight Journal, vol. ISC/NAMIC/ MICCAI Workshop on Open-Source Software, 2005, Online publication: http://hdl.handle.net/1926/39 .
 
  
 
</div>
 
</div>

Latest revision as of 10:45, 25 June 2010

Home < 2010 NAMIC Project week:LongitudinalPETSUV Wizard

  • PET

  • ROI

  • SUV

Back to NA-MIC Kit Internals, Summer Project Week 2010

Key Investigators

  • BWH: Wendy Plesniak, Alex Zaitsev, Ron Kikinis

Objective

We are developing a Slicer command-line module for PET SUV computation and a wizard interface to a specific workflow for PET SUV computation for longitudinal studies.




Approach, Plan

Our approach will be very similar to the ChangeTracker wizard in Slicer3.

Our plan for the project week is to

  • design the steps of the workflow
  • implement the GUI
  • implement the MRML nodes to hold state
  • discuss design of proper (CLI) interfaces to workflow engine
  • and begin to hook up logic, mrml and gui.

Progress

  • Commandline Module for SUV computation with multiple VOIs, multiple timepoints started. Close to being finished and will provide a calling convention for Alex to use in his workflow engine.

Delivery Mechanism

This work will be delivered to the NA-MIC Kit as a built-in module in Slicer3.7

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