Difference between revisions of "2013 Project Week:PkModeling for prostate DCE MRI"
From NAMIC Wiki
(Created page with '__NOTOC__ <gallery> Image:PW-SLC2013.png|Projects List </gallery> ==Key Investigators== * BWH: Andrey Fedorov * GE: Jim Miller ==Project D…') |
|||
| (One intermediate revision by the same user not shown) | |||
| Line 23: | Line 23: | ||
<div style="width: 27%; float: left; padding-right: 3%;"> | <div style="width: 27%; float: left; padding-right: 3%;"> | ||
<h3>Progress</h3> | <h3>Progress</h3> | ||
| − | + | * The main source of the inconsistency was due to different models used by the two tools being compared: 2-parameter (Ktrans+ve) vs 3-parameter (Ktrans+ve+fpv). After fixing this, the results were very similar (difference <1% vs 1000%). | |
| + | * Bolus arrival time was not estimated in the Slicer PkModeling tool. | ||
| + | * Work in progress: | ||
| + | ** Andrey: update the code to propagate model selection through various layers/filters of the module | ||
| + | ** Jim: look into the issue of synchronizing bolus arrival time for the plasma/tissue curves | ||
</div> | </div> | ||
</div> | </div> | ||
Latest revision as of 00:16, 11 January 2013
Home < 2013 Project Week:PkModeling for prostate DCE MRI
Key Investigators
- BWH: Andrey Fedorov
- GE: Jim Miller
Project Description
Objective
- debug and test the pharmacokinetic modeling extension on prostate DCE MRI data
Approach, Plan
- previously validated non-open-source implementation of the PK modeling will be used as reference for comparison with the results produced by PkModeling extension
- prostate DCE MRI data will be used for testing using identically defined AIF
- success will be achieved if the results produced by PkModeling and the reference software agree
Progress
- The main source of the inconsistency was due to different models used by the two tools being compared: 2-parameter (Ktrans+ve) vs 3-parameter (Ktrans+ve+fpv). After fixing this, the results were very similar (difference <1% vs 1000%).
- Bolus arrival time was not estimated in the Slicer PkModeling tool.
- Work in progress:
- Andrey: update the code to propagate model selection through various layers/filters of the module
- Jim: look into the issue of synchronizing bolus arrival time for the plasma/tissue curves
