Difference between revisions of "2013 Summer Project Week:Proton dose calculation"

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<gallery>
 
<gallery>
 
Image:PW-MIT2013.png|[[2013_Summer_Project_Week#Projects|Projects List]]
 
Image:PW-MIT2013.png|[[2013_Summer_Project_Week#Projects|Projects List]]
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Image:genuFAp.jpg|Scatter plot of the original FA data through the genu of the corpus callosum of a normal brain.
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Image:2013_Summer_Project_Week_Proton_Dose_1.jpg| Aperture and range compensator
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Image:genuFA.jpg|Regression of FA data; solid line represents the mean and dotted lines the standard deviation.
 
 
</gallery>
 
</gallery>
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==Instructions for Use of this Template==
 
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#Please create a new wiki page with an appropriate title for your project using the convention 2013_Summer_Project_Week:<Project Name>
 
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#Copy the entire text of this page into the page created above
 
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#Link the created page into the list of projects for the project event
 
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#Delete this section from the created page
 
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#Send an email to tkapur at bwh.harvard.edu if you are stuck
 
  
 
==Key Investigators==
 
==Key Investigators==
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* UNC: Isabelle Corouge, Casey Goodlett, Guido Gerig
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* MGH: Greg Sharp, Maxime Desplanques
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* Utah: Tom Fletcher, Ross Whitaker
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* PMH: Kevin Wang
  
 
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<h3>Objective</h3>
 
<h3>Objective</h3>
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We are developing methods for analyzing diffusion tensor data along fiber tracts. The goal is to be able to make statistical group comparisons with fiber tracts as a common reference frame for comparison.
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We are developing an external-beam proton dose calculation module for 3D Slicer.
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<h3>Approach, Plan</h3>
 
<h3>Approach, Plan</h3>
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Make edits to plastimatch and SlicerRT codes to implement aperture definition, range compensator
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Our approach for analyzing diffusion tensors is summarized in the IPMI 2007 reference below.  The main challenge to this approach is <foo>.
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definition, and SOBP optimization code and
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return resulting calculation to Slicer.
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Our plan for the project week is to first try out <bar>,...
 
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<h3>Progress</h3>
 
<h3>Progress</h3>
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Software for the fiber tracking and statistical analysis along the tracts has been implemented. The statistical methods for diffusion tensors are implemented as ITK code as part of the [[NA-MIC/Projects/Diffusion_Image_Analysis/DTI_Software_and_Algorithm_Infrastructure|DTI Software Infrastructure]] project. The methods have been validated on a repeated scan of a healthy individual. This work has been published as a conference paper (MICCAI 2005) and a journal version (MEDIA 2006). Our recent IPMI 2007 paper includes a nonparametric regression method for analyzing data along a fiber tract.
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* Read SlicerRT contour as labelmap - Done
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* Create aperture and range compensator - Done
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* Display aperture and range compensator in Slicer - Done
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* Generate optimal SOBP - TODO
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* Generate dose in Slicer - TODO
 
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##Built-in
 
##Built-in
 
##Extension -- commandline
 
##Extension -- commandline
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##Extension -- loadable
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##Extension -- loadable (YES)
 
#Other (Please specify)
 
#Other (Please specify)
  
 
==References==
 
==References==
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*Fletcher P, Tao R, Jeong W, Whitaker R. [http://www.na-mic.org/publications/item/view/634 A volumetric approach to quantifying region-to-region white matter connectivity in diffusion tensor MRI.] Inf Process Med Imaging. 2007;20:346-358. PMID: 17633712.
 
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* Corouge I, Fletcher P, Joshi S, Gouttard S, Gerig G. [http://www.na-mic.org/publications/item/view/292 Fiber tract-oriented statistics for quantitative diffusion tensor MRI analysis.] Med Image Anal. 2006 Oct;10(5):786-98. PMID: 16926104.
 
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* Corouge I, Fletcher P, Joshi S, Gilmore J, Gerig G. [http://www.na-mic.org/publications/item/view/1122 Fiber tract-oriented statistics for quantitative diffusion tensor MRI analysis.] Int Conf Med Image Comput Comput Assist Interv. 2005;8(Pt 1):131-9. PMID: 16685838.
 
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* Goodlett C, Corouge I, Jomier M, Gerig G, A Quantitative DTI Fiber Tract Analysis Suite, The Insight Journal, vol. ISC/NAMIC/ MICCAI Workshop on Open-Source Software, 2005, Online publication: http://hdl.handle.net/1926/39 .
 

Latest revision as of 18:43, 20 June 2013

Home < 2013 Summer Project Week:Proton dose calculation

Key Investigators

  • MGH: Greg Sharp, Maxime Desplanques
  • PMH: Kevin Wang

Objective

We are developing an external-beam proton dose calculation module for 3D Slicer.

Approach, Plan

Make edits to plastimatch and SlicerRT codes to implement aperture definition, range compensator definition, and SOBP optimization code and return resulting calculation to Slicer.

Progress

  • Read SlicerRT contour as labelmap - Done
  • Create aperture and range compensator - Done
  • Display aperture and range compensator in Slicer - Done
  • Generate optimal SOBP - TODO
  • Generate dose in Slicer - TODO

Delivery Mechanism

This work will be delivered to the NA-MIC Kit as a (please select the appropriate options by noting YES against them below)

  1. ITK Module
  2. Slicer Module
    1. Built-in
    2. Extension -- commandline
    3. Extension -- loadable (YES)
  3. Other (Please specify)

References

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