Difference between revisions of "NA"

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'''Objective:''' The Slicer3 Execution Model realizes the "Extensible Algorithmic Framework" goal by providing an interactive point-and-click interface to ITK-based command line executables, LONI Pipelines, and Grid Services without extensive re-engineering by the algorithm developer. The Execution Model uses an XML syntax to describe algorithm options and user interface controls. Slicer3 constructs the appropriate user interfaces from this description and manages the data transfer to and from the algorithm module. Such processing modules can be discovered at runtime and delivered to clinicians as plugins to Slicer3.
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'''Objective:''' To improve shape analysis of the caudate and to parcellate the corpus callosum based on function.
  
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'''Progress:''' An initial implementation is complete and under evaluation. The command line processing is automatically generated from the XML decription file. The generation process has been added to CMake.
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'''Progress:'''
  
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'''Key Investigators'''<nowiki>: </nowiki>
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* UNC applied shape analysis pipeline to a dataset of manually segmented caudates of males with and without schizoptypal personality disorders. Differences were found mainly on the right caudates. No differences were found for regional parcellations of the corpus callosum.
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* The open source shape analysis pipeline was transfered and installed at Harvard PNL.
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* Harvard applied the UNC shape analysis software to a new dataset of manually segmented caudates of females with and without schizotypal personality disorder. The results confirmed previous findings in the male dataset. Statistically significant shape differences for the right caudate were found (see Fig 1).
  
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* Dan Blezek, Jim Miller and Bill Lorensen (GE)
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'''Key Investigators:'''
  
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Links: [[Slicer3:Execution_Model|Slicer3:Execution_Model]]
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* Harvard PNL: Sylvain Bouix, Marek Kubicki, James Levitt, Marc Niethammer, Martha Shenton
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* UNC: Martin Styner, Isabelle Corouge, Guido Gerig
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* Georgia Tech: Delphine Nain, Allen Tannenbaum
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{|
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|+ '''Fig 1. Right female caudate results'''
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|-
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| valign="top" |
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<div class="thumb tright"><div style="width: 252px">[[Image:Rawpval_rc_back_min.png|[[Image:250px-Rawpval_rc_back_min.png|Medial]]]]<div class="thumbcaption"><div class="magnify" style="float: right">[[Image:Rawpval_rc_back_min.png|[[Image:magnify-clip.png|Enlarge]]]]</div>Medial</div></div></div>
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| valign="top" |
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<div class="thumb tright"><div style="width: 277px">[[Image:Rawpval_rc_front_min.png|[[Image:275px-Rawpval_rc_front_min.png|Lateral]]]]<div class="thumbcaption"><div class="magnify" style="float: right">[[Image:Rawpval_rc_front_min.png|[[Image:magnify-clip.png|Enlarge]]]]</div>Lateral</div></div></div>
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| valign="top" |
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<div class="thumb tright"><div style="width: 52px">[[Image:Rawpval_rc_colorbar_min.png|[[Image:50px-Rawpval_rc_colorbar_min.png|p value]]]]<div class="thumbcaption"><div class="magnify" style="float: right">[[Image:Rawpval_rc_colorbar_min.png|[[Image:magnify-clip.png|Enlarge]]]]</div>p value</div></div></div>
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|}
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'''Links:'''
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* [[Progress_Report:Shape_Analysis|Shape Analysis Progress Report]]
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* [[DBP:Harvard:Collaboration:UNC|DBP:Harvard:Collaboration:UNC]]
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* [[DataRepository#Brockton_VA.2FHarvard_Structural_and_DTI_Images|Male caudate data]]

Revision as of 13:28, 18 December 2006

Home < NA

Objective: To improve shape analysis of the caudate and to parcellate the corpus callosum based on function.

Progress:

  • UNC applied shape analysis pipeline to a dataset of manually segmented caudates of males with and without schizoptypal personality disorders. Differences were found mainly on the right caudates. No differences were found for regional parcellations of the corpus callosum.
  • The open source shape analysis pipeline was transfered and installed at Harvard PNL.
  • Harvard applied the UNC shape analysis software to a new dataset of manually segmented caudates of females with and without schizotypal personality disorder. The results confirmed previous findings in the male dataset. Statistically significant shape differences for the right caudate were found (see Fig 1).

Key Investigators:

  • Harvard PNL: Sylvain Bouix, Marek Kubicki, James Levitt, Marc Niethammer, Martha Shenton
  • UNC: Martin Styner, Isabelle Corouge, Guido Gerig
  • Georgia Tech: Delphine Nain, Allen Tannenbaum
Fig 1. Right female caudate results
Medial
Enlarge
Medial
Lateral
Enlarge
Lateral
p value
Enlarge
p value

Links:

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