Difference between revisions of "NA"

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'''Objective:''' Develop the next generation biomedical computing application platform using NA-MIC kit software technologies developed in Years 1 & 2 of the NA-MIC project.
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'''Objective:''' This project assesses working memory using an auditory verbal version of the n-back task paradigm. Three conditions are presented in blocks in counterbalanced order with increasing working memory load demands (0-, 1-, 2- and 3-back). We will use NAMIC tools to perform novel analyses of the relationships between brain activation and morphological data (e.g., ROI volumes, DTI) in order to improve our understanding of structure-function relationships and connectivity in schizophrenia.
  
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'''Progress:'''
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'''Progress:''' To date, 16 patients with schizophrenia and 13 healthy controls have been studied. Preliminary analyses on a subgroup have been completed (see image below). Data will be available in year three.
  
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* Implementation (alpha stage: compile and run) of a base object hierachy with smart pointer, timestamp, factory, tcl wrapping for an independant MRML lib. Allow separation of mrml from vtkmrml, and itkmrml.
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[[Image:NAMIC_prelim_n2bk_results_good.jpg|[[Image:NAMIC_prelim_n2bk_results_good.jpg|Image:NAMIC_prelim_n2bk_results_good.jpg]]]]
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* Developed design and initial implementation of module loading facility.
 
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* Developed undo/redo facility for MRML data library.
 
  
 
'''Key Investigators:'''
 
'''Key Investigators:'''
  
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* Isomics: Steve Pieper, Alex Yarmarkovich
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* Dartmouth: Andrew Saykin, Robert Roth, Laura Flashman, John West, Thomas McAllister
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* Kitware: Mathieu Malaterre, Sebastien Barre
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* Harvard: Martha Shenton, Marek Kubicki
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* GE: Bill Lorensen, Jim Miller, Dan Blezek, Xiaodong Tao
 
  
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'''Links:'''
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'''Links'''
  
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* MRML reimplementation proposal: [[User:Mathieu/Slicer|User:Mathieu/Slicer]]
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* [[DBP:Marek_Kubicki_visit_Dartmouth_December_20_2005|December 20, 2005: Marek Kubicki visit to Dartmouth]]
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* [http://www.na-mic.org:8000/websvn/listing.php?repname=Slicer3 Slicer3 websvn]
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* [[DBP:Andy_Saykin_visit_BWH_December_14_2005|December 14, 2005: Andy Saykin and Group visit to Brigham and Women's Hospital]]
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* [http://www.na-mic.org:8000/websvn/listing.php?repname=NAMICSandBox&path=%2Ftrunk%2FSlicer30Architecture%2FDataModelManager%2Fmrml%2F libMRML proposal]
 

Revision as of 14:03, 18 December 2006

Home < NA

Objective: This project assesses working memory using an auditory verbal version of the n-back task paradigm. Three conditions are presented in blocks in counterbalanced order with increasing working memory load demands (0-, 1-, 2- and 3-back). We will use NAMIC tools to perform novel analyses of the relationships between brain activation and morphological data (e.g., ROI volumes, DTI) in order to improve our understanding of structure-function relationships and connectivity in schizophrenia.

Progress: To date, 16 patients with schizophrenia and 13 healthy controls have been studied. Preliminary analyses on a subgroup have been completed (see image below). Data will be available in year three.

Key Investigators:

  • Dartmouth: Andrew Saykin, Robert Roth, Laura Flashman, John West, Thomas McAllister
  • Harvard: Martha Shenton, Marek Kubicki

Links

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