Difference between revisions of "Projects:NeuralSubstratesOfWorkingMemoryInSchizophrenia"

From NAMIC Wiki
Jump to: navigation, search
m (Update from Wiki)
 
m
Line 8: Line 8:
  
 
* Dartmouth: Andrew Saykin, Robert Roth, Laura Flashman, John West, Thomas McAllister
 
* Dartmouth: Andrew Saykin, Robert Roth, Laura Flashman, John West, Thomas McAllister
* Harvard: Martha Shenton, Marek Kubicki
+
* BWH: Martha Shenton, Marek Kubicki
  
 
'''Links'''
 
'''Links'''

Revision as of 16:29, 3 May 2007

Home < Projects:NeuralSubstratesOfWorkingMemoryInSchizophrenia

Objective: This project assesses working memory using an auditory verbal version of the n-back task paradigm. Three conditions are presented in blocks in counterbalanced order with increasing working memory load demands (0-, 1-, 2- and 3-back). We will use NAMIC tools to perform novel analyses of the relationships between brain activation and morphological data (e.g., ROI volumes, DTI) in order to improve our understanding of structure-function relationships and connectivity in schizophrenia.

Progress: To date, 16 patients with schizophrenia and 13 healthy controls have been studied. Preliminary analyses on a subgroup have been completed (see image below). Data will be available in year three.

Key Investigators:

  • Dartmouth: Andrew Saykin, Robert Roth, Laura Flashman, John West, Thomas McAllister
  • BWH: Martha Shenton, Marek Kubicki

Links