Difference between revisions of "Projects:NeuralSubstratesOfWorkingMemoryInSchizophrenia"
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* Dartmouth: Andrew Saykin, Robert Roth, Laura Flashman, John West, Thomas McAllister | * Dartmouth: Andrew Saykin, Robert Roth, Laura Flashman, John West, Thomas McAllister | ||
− | * | + | * BWH: Martha Shenton, Marek Kubicki |
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Revision as of 16:29, 3 May 2007
Home < Projects:NeuralSubstratesOfWorkingMemoryInSchizophreniaObjective: This project assesses working memory using an auditory verbal version of the n-back task paradigm. Three conditions are presented in blocks in counterbalanced order with increasing working memory load demands (0-, 1-, 2- and 3-back). We will use NAMIC tools to perform novel analyses of the relationships between brain activation and morphological data (e.g., ROI volumes, DTI) in order to improve our understanding of structure-function relationships and connectivity in schizophrenia.
Progress: To date, 16 patients with schizophrenia and 13 healthy controls have been studied. Preliminary analyses on a subgroup have been completed (see image below). Data will be available in year three.
Key Investigators:
- Dartmouth: Andrew Saykin, Robert Roth, Laura Flashman, John West, Thomas McAllister
- BWH: Martha Shenton, Marek Kubicki
Links