Difference between revisions of "Projects:BrainActivationDuringContinuousVerbalEncodingAndRecognitionTaskInSchizophrenia"

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= Brain Activation during Continuous Verbal Encoding and Recognition Task in Schizophrenia =
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  Back to [[NA-MIC_Collaborations|NA-MIC_Collaborations]]
 
  Back to [[NA-MIC_Collaborations|NA-MIC_Collaborations]]
  
'''Objective:''' This project employs an event-related auditory verbal episodic memory probe targeting medial temporal and DLPFC circuitry. The task uses a continuous performance format where concrete nouns are presented initially as new items. Words are then repeated after short or long intervals and the participant is required to make a new/old distinction. This design permits analysis of both encoding and recognition processes.
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'''Objective'''  
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This project employs an event-related auditory verbal episodic memory probe targeting medial temporal and DLPFC circuitry. The task uses a continuous performance format where concrete nouns are presented initially as new items. Words are then repeated after short or long intervals and the participant is required to make a new/old distinction. This design permits analysis of both encoding and recognition processes.
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'''Progress'''
  
'''Progress:''' To date, data have been collected on 8 patients with schizophrenia and 5 healthy controls. Preliminary analysis on a subset of this data has been completed (see figure below). Sample data is available and more data will become available in year three.
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To date, data have been collected on 8 patients with schizophrenia and 5 healthy controls. Preliminary analysis on a subset of this data has been completed (see figure below). Sample data is available and more data will become available in year three.
  
 
[[Image:NAMIC_AVrecog_prelim_results.jpg|[[Image:NAMIC_AVrecog_prelim_results.jpg|Image:NAMIC_AVrecog_prelim_results.jpg]]]]
 
[[Image:NAMIC_AVrecog_prelim_results.jpg|[[Image:NAMIC_AVrecog_prelim_results.jpg|Image:NAMIC_AVrecog_prelim_results.jpg]]]]
  
'''Year Three Update:'''
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''Year Three Update''
 
Data collection and analysis is ongoing.  Updated results are expected at the end of year three.
 
Data collection and analysis is ongoing.  Updated results are expected at the end of year three.
  
'''Key Investigators:'''
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'''Key Investigators'''
  
 
* Dartmouth: Andrew Saykin, Robert Roth, Laura Flashman, John West, Thomas McAllister
 
* Dartmouth: Andrew Saykin, Robert Roth, Laura Flashman, John West, Thomas McAllister

Revision as of 02:09, 4 September 2007

Home < Projects:BrainActivationDuringContinuousVerbalEncodingAndRecognitionTaskInSchizophrenia

Brain Activation during Continuous Verbal Encoding and Recognition Task in Schizophrenia

Back to NA-MIC_Collaborations

Objective

This project employs an event-related auditory verbal episodic memory probe targeting medial temporal and DLPFC circuitry. The task uses a continuous performance format where concrete nouns are presented initially as new items. Words are then repeated after short or long intervals and the participant is required to make a new/old distinction. This design permits analysis of both encoding and recognition processes.

Progress

To date, data have been collected on 8 patients with schizophrenia and 5 healthy controls. Preliminary analysis on a subset of this data has been completed (see figure below). Sample data is available and more data will become available in year three.

Year Three Update Data collection and analysis is ongoing. Updated results are expected at the end of year three.

Key Investigators

  • Dartmouth: Andrew Saykin, Robert Roth, Laura Flashman, John West, Thomas McAllister
  • Harvard: Martha Shenton, Marek Kubicki

Links