Difference between revisions of "Mbirn: MBIRNCollab"

From NAMIC Wiki
Jump to: navigation, search
m (Update from Wiki)
m (Update from Wiki)
Line 1: Line 1:
 
* '''Reference:''' [http://www.nmr.mgh.harvard.edu/~jovicich/MorphBIRN_reminder_updates.htm#_Toc91037736 Proposed Collaborations]
 
* '''Reference:''' [http://www.nmr.mgh.harvard.edu/~jovicich/MorphBIRN_reminder_updates.htm#_Toc91037736 Proposed Collaborations]
  
−
* '''Updated March 28, 2006 (original entry Feb 17, 2005)''' (C. Fennema Notestine)
+
* '''Feb 11, 2005''' (J. MacFall)
−
 
+
** Project #10: Funded, this is where the original MIRIAD data comes from. Paper being prepared with lobar analysis.
−
* ** '''Project #5 NIA/ADRC''' (UCSD/L. Thal & T. Jernigan: legacy T1, clinical, neuropsych AD and controls):
+
** Project #11: Funded and ongoing. 3T, heavy DTI component. Will bring this up at Miami meeting to discuss with Anders & Allen re suggested protocols. This is a 5-year project that will acquire 60 subj/year. Use of BIRN can come in the form of protocol suggestions, data analysis and maybe also for data sharing.
−
*** See on-going mBIRN MAD study at MBIRN project page [[Multi-site_AD|Multi-site AD]].
+
** Project #13: Not funded
−
 
+
** Project #17: MCI multi-site Novartis. More on this is listed under [[MBIRNCollab-UCI]]
−
* ** '''Project #12 NIA/VETSA''' (UCSD/W. Kremen: longitudinal, multi-site (UCSD and MGH) study; T1, T2, and DTI, neuropsych, clinical assessment, genetic Vietnam-era (male-male) twins from the VA twin registry (expected n=300 pairs, half at each site) a nationwide sample):
+
** Not listed in proposal: ENCOT study. Longitudinal, 1.5T, elderly depressed, 10-year project at this point. Will use MIRIAD pipeline (lobar analysis). James is starting this now as the first MIRIAD lobar paper is getting finished.
−
*** On-going study is collecting Siemens 1.5T scans at UCSD and MGH with approx. 330 datasets to date.
 
−
*** Data acquisition and gradient distortion correction are facilitated by BIRN protocols to ensure that all data are acquired using the same parameters and settings to allow comparability of data.
 
−
*** Structural MR analysis with FreeSurfer underway for subcortical segmentation and cortical parcellation.
 
−
*** DTI analysis path development on-going with mBIRN initiatives (see [[Mbirn:_MRI_Diffusion_Tools|Mbirn: MRI Diffusion Tools]]).
 
−
*** Neuropsychological and cortisol studies also on-going.
 
−
 
 
−
* ** '''Project #13 NIA/ADNI''' (UCSF/Weiner; UCSD/Dale: longitudinal, multi-site (60 sites) study; T1, T2, PET, clinical and genetic AD (n=200), MCI (n=400) and controls (n=200) each scanned 5-7 times across 5 years. Expect 4200 total data sets):
 
−
*** ADNI project has completed the first year preparation phase and begun data collection for the execution phase.
 
−
*** Calibration and distortion correction have incorporated BIRN tools and approaches (see [[Reproducibility_of_T1-based_multispectral_data_%26_derived_morphometry|Reproducibility of T1-based multispectral data & derived morphometry]]).
 
−
*** mBIRN is working with ADNI to propose further collaborative efforts.
 
−
 
 
−
* ** '''Project #14 NIMH/CHARTER''' (UCSD/I. Grant & T. Jernigan - CNS HIV Anti-retroviral Therapy Effects Research: longitudinal, multi-site study; T1, T2, PD, MRS (and DTI at UCSD), clinical, treatment response, CSF HIV RNA, CD4 AIDS patients with and without dementia):
 
−
*** CHARTER study aims to examine white and gray matter changes in HIV and the relationship of these changes to treatment regimens.
 
−
*** There are five national sites (all GE 1.5T systems), the center is located here at UCSD, and the project is now in the data collection phase for first year followup scans.
 
−
*** mBIRN has consulted with CHARTER regarding gradient distortion correction in a combined image set of 3D T1/PD and 2D T2/PD volumes.
 
−
*** Future collaborative aims are related to the integration of complementary tools for analysis of multi-spectral data that aims to capture these white matter changes more automatically, with the local group of investigators (R. Notestine, A. Gamst, A. Dale).
 
  
 
<br />
 
<br />
−
 
−
<br /> Back to [[Mbirn:_Clinical_Collaborations|Mbirn: Clinical Collaborations]]
 

Revision as of 14:09, 18 December 2006

Home < Mbirn: MBIRNCollab
  • Feb 11, 2005 (J. MacFall)
    • Project #10: Funded, this is where the original MIRIAD data comes from. Paper being prepared with lobar analysis.
    • Project #11: Funded and ongoing. 3T, heavy DTI component. Will bring this up at Miami meeting to discuss with Anders & Allen re suggested protocols. This is a 5-year project that will acquire 60 subj/year. Use of BIRN can come in the form of protocol suggestions, data analysis and maybe also for data sharing.
    • Project #13: Not funded
    • Project #17: MCI multi-site Novartis. More on this is listed under MBIRNCollab-UCI
    • Not listed in proposal: ENCOT study. Longitudinal, 1.5T, elderly depressed, 10-year project at this point. Will use MIRIAD pipeline (lobar analysis). James is starting this now as the first MIRIAD lobar paper is getting finished.


Retrieved from "https://www.na-mic.org/w/index.php?title=Mbirn:_MBIRNCollab&oldid=4549"