Difference between revisions of "Projects:RegistrationLibrary:RegLib C08"
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{| style="color:#bbbbbb; background-color:#333333;" cellpadding="10" cellspacing="0" border="0" | {| style="color:#bbbbbb; background-color:#333333;" cellpadding="10" cellspacing="0" border="0" | ||
| − | |[[Image:RegLib_C08_CT1_thumbnail.png| | + | |[[Image:RegLib_C08_CT1_thumbnail.png|100px|lleft|this is the fixed reference image. All images are aligned into this space]] |
| − | |[[Image:RegLib_C08_PET1_thumbnail.png| | + | |[[Image:RegLib_C08_PET1_thumbnail.png|100px|lleft|this is also a fixed reference image. All images are aligned into this space]] |
|[[Image:Arrow_left_gray.jpg|100px|lleft]] | |[[Image:Arrow_left_gray.jpg|100px|lleft]] | ||
| − | |[[Image:RegLib_C08_CT2_thumbnail.png| | + | |[[Image:RegLib_C08_CT2_thumbnail.png|100px|lleft|this is the moving image. The transform is calculated by matching this to the reference image]] |
| − | |[[Image:RegLib_C08_PET2_thumbnail.png| | + | |[[Image:RegLib_C08_PET2_thumbnail.png|100px|lleft|this is a passivley (tag) image. The calculated transforms are applied to this image]] |
|align="left"|LEGEND<br> | |align="left"|LEGEND<br> | ||
[[Image:Button_red_fixed.jpg|20px|lleft]] this indicates the reference image that is fixed and does not move. All other images are aligned into this space and resolution<br> | [[Image:Button_red_fixed.jpg|20px|lleft]] this indicates the reference image that is fixed and does not move. All other images are aligned into this space and resolution<br> | ||
Revision as of 17:29, 19 March 2010
Home < Projects:RegistrationLibrary:RegLib C08Back to ARRA main page
Back to Registration main page
Back to Registration Use-case Inventory
Contents
Slicer Registration Use Case Exampe #8: Intra-subject whole-body PET-CT
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LEGEND
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 whole body CT baseline
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whole body PET baseline
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 whole body CT follow-up
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 whole body PET follow-up
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| CT: 512 x 512 x 267 0.97 x 0.97 x 3.27 mm |
PET: 128 x 128 x 267 4.7 x 4.7 x 3.3 mm |
CT: 512 x 512 x 195 0.98 x 0.98 x 5.0 mm |
PET: 168 x 168 x 195 4.1 x 4.1 x 5 mm |
Objective / Background
Change assessment.
Keywords
PET-CT, whole-body, change assessment
Input Data
reference/fixed : baseline CT: 0.97 x 0.97 x 3.27 mm , PET: 4.7 x 4.7 x 3.3 mm
moving: CT: 0.98 x 0.98 x 5
moving: PET: 4.1 x 4.1 x 5 mm
Registration Results
Download
Link to User Guide: How to Load/Save Registration Parameter Presets
Discussion: Registration Challenges
- accuracy is the critical criterion here. We need the registration error (residual misalignment) to be smaller than the change we want to measure/detect. Agreement on what constitutes good alignment can therefore vary greatly.
- the two series have different voxel sizes
- because of the large FOV we have strong non-rigid deformations from differences in patient/limb positions etc.
- images are large volumes (>100 MB total)
- image content reaches border of image on two sides
Discussion: Key Strategies
- the two images have identical contrast, hence we can consider "sharper" cost functions, such as NormCorr or MeanSqrd
- the contrast differences between the PET and CT far exceed the longitudinal differences in either modality. Hence, if necessary we can take advantage by registering each series separately and then build a concatenated transform.
- the two images are far apart initially, we will need some form of initialization. Manual alignment is a fast and effective approach for this.
- because accuracy is more important than speed here, we increase the sampling rate from the default 2% to 15%. Note however the large image size, which makes comparable sampling % still large compared to other datasets.
