Revision as of 17:15, 11 November 2010

Home < Projects:SlicerFAQ:DWI Registration

How do I register a DWI/DTI image to a reference image ?

Problem: The DWI/DTI image is not in the same orientation as the reference image that I would like to use to locate particular anatomy; the DWI image is distorted and does not line up well with the structural images
Explanation: DWI images are often acquired as EPI sequences that contain significant distortions, particularly in the frontal areas. Also because the image is acquired before or after the structural scans, the subject may have moved in between and the position is no longer the same.
Fix: obtain a baseline image from the DWI sequence, register that with the structural image and then apply the obtained transform to the DTI tensor. The two chief issues with this procedure deal with the difference in image contrast between the DWI and the structural scan, and with the common anisotropy of DWI data.

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you can find example cases of DWI registration in the Slicer Registration Case Library, which includes example datasets and step-by-step instructions. Find an example closest to your scenario and perform the registration steps recommended there.

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		+	* you can find example cases of DWI registration in the [http://na-mic.org/Wiki/index.php/Projects:RegistrationDocumentation:UseCaseInventory:BrainIntraDTI\|'''Slicer Registration Case Library''], which includes example datasets and step-by-step instructions. Find an example closest to your scenario and perform the registration steps recommended there.