NA-MIC/Projects/External Collaboration/W&M CRTC
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Key Investigators
- Nikos Chrisochoides, CRTC (Project lead)
- Andrey Fedorov, CRTC
- Luis Ibanez, Kitware
- Jim Miller, Kitware
- Dan Marcus
- Tina Kapur
- Marcel Prastawa
Objective
The mission of the Center for Real-Time Computing is to promote innovation in time critical applications like medical image analysis for Image Guided Therapy. The application of our focus is non-rigid image registration (NRR) for image-guided neurosurgery. The objective is to improve the performance, accuracy and usability of the existing method. There are two sub-projects we plan to explore.
1. Distributed parametric search for optimum parameter setting during NRR. This project includes three components: 1) development/evaluation of tools and methods for automated registration validation; 2) collection of ground truth data sets; 3) development of the high performance computing infrastructure.
2. Tetrahedral mesh generation for intra-cranial cavity discretization used in physics-based NRR.
Approach, Plan
1. Distributed parametric search:
- need help with automated validation approaches, neurosurgery datasets
- evaluate the infrastructure options: GWE/GSlicer3? web portal? TeraGrid?
- are there other needs for this kind of large-scale computing?
2. Tetrahedral mesh generation:
- meshing TCON Jun 19: no volume mesh generation discussed. What is (is there?) the need for tetrahedral mesh generation from NA-MIC projects?
- status of unstructured grid visualization in Slicer3
- meshing as a plugin in Slicer3
Progress
1. Distributed parameter search for NRR:
- missing features in GWE: support for MPI process execution and flow (dependencies) control
- work in progress: scripts for remote submission and execution on TeraGrid (execution module integration of the front end for registration with Slicer complete earlier)
- new datasets for registration evaluation: MRT data from XNAT, tumor growth for NRR validation (Utah)
2 (Tetrahedral) mesh generation:
- very limited open source support, limited mesh generation functionality in ITK/VTK
- identified a group of applications that require meshing, continue discussion
- Slicer3 meshing integration: vtkUnstructuredGrid support almost ready in Slicer
Funding
This work is supported in part by NSF grant CSI-719929 and by John Simon Guggenheim Memorial Foundation.
