Projects:SlicerFAQ

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  • How do I fix an wrong orientation of a loaded image volume? / My image appears upside down / facing the wrong way / I have incorrect/missing axis orientation
    • Slicer presents and interacts with images in 'physical space, which differs from the way the image is stored by a separate transform that defines how large the voxels are and how the image is oriented in space, e.g. which side is left or right. This information is stored in the image header, and different image file formats have different ways of storing this information. If Slicer supports the image format, it should read the information in the header and display the image correctly. If the image appears upside down or with distorted aspect ratio etc, then the image header information is either missing or incorrect. You can correct the voxel dimensions and the image origin in the Info tab of the Volumes module, and you can reorient images via the Transforms module. Reorientation however will work only if the incorrect orientation involves rotation or translation. If axes are flipped (e.g. if left & right are flipped because the x-axis direction is defined incorrectly), then there is no tool in Slicer to alter that. This is by design; Slicer does not want to offer tools to (inadvertedly) manipulate image information that should be static and could lead to misrepresented image data. However fixing incorrect orientations such as flipped axes is not that hard and can be done with the help of Slicer:
  1. load the image into slicer (Load Volume, Add Data,Load Scene..)
  2. save the image back out as .nhdr format.
  3. open the .nhdr with a text editor of your choice. You should see a line that looks like this:
 space: left-posterior-superior
 sizes: 448 448 128
 space directions: (0.5,0,0) (0,0.5,0) (0,0,0.8)


  • what do the coordinate labels R,A,S and (negative numbers) mean?
  • Loaded images are very far apart
  • How do I fix incorrect voxel size / aspect ratio of a loaded image volume?
  • How do I register a DWI image dataset to a structural reference scan? -> (Cookbook)
  • Can I manually adjust a registration?
  • What's the difference between the various registration methods listed in Slicer?
  • What's the purpose of masking / VOI in registration?
  • Registration failed with an error. What should I try next?
  • Registration result is wrong or worse than before?
  • I want to register two images with different intensity/contrast
  • how important is bias field correction / intensity inhomogeneity correction?
  • what is the purpose of masking?