2009 Summer Project Week Adaptive RT

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Key Investigators

  • GaTech: Ivan Kolesov, Vandana Mohan, and Allen Tannenbaum
  • MGH: Gregory Sharp

Objective

We are developing strategies to perform segmentation of a number of structures in the Head, Neck, and Thorax. Once segmentation is available, the goal is to register patient scans to account for anatomical changes between visits.




Approach, Plan

  • Get an accurate segmentation before beginning work on registration
  • First structure of interest is the mandible, by the end of the project week, obtain its segmentation
  • Come up with a strategy for segmenting the brain stem
  • Create an outline for further progress after the project week


Progress

Software for the fiber tracking and statistical analysis along the tracts has been implemented. The statistical methods for diffusion tensors are implemented as ITK code as part of the DTI Software Infrastructure project. The methods have been validated on a repeated scan of a healthy individual. This work has been published as a conference paper (MICCAI 2005) and a journal version (MEDIA 2006). Our recent IPMI 2007 paper includes a nonparametric regression method for analyzing data along a fiber tract.