Projects:ShapeAnalysisOfHippocampus

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Objective: To examine hippocampal shape in patients with schizophrenia and healthy controls.

Progress:

• Initial hippocampal segmentations of healthy control data were successfully processed at UNC (see average asymmetry as examplary analysis in Fig 2.)
• Data has been acquired at 1.5T on 20 patients with schizophrenia and 20 healthy controls at Dartmouth.
• Have begun to apply 3D Slicer for manual segmentation. Additional subject accrual ongoing.

Key Investigators:

• Dartmouth: Andrew Saykin, Tara McHugh, Robert Roth, Laura Flashman
• Harvard: Steve Pieper
• UNC: Martin Styner, Guido Gerig

Fig 1. Healthy Asymmetry results

Links:

• Shape Analysis Progress Report
• Data Repository for this preliminary analysis