2010 Winter Project Week Tractography using DTI Atlasing

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  Projects List

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Key Investigators

• Utah: Gopalkrishna Veni, Ross Whitaker, Sarang Joshi

Objective

To study the effect of drugs on teenagers in the age group of 12-30.

Approach, Plan

Initially, the DWI data is preprocessed to address Eddy current correction and EPI distortion correction. Next, DTI Atlas building is performed using Casey’s DTI analysis pipeline* to bring all the DTI images into a common co-ordinate system and then fiber tract analysis is performed to compare the differences in specific fiber tracts. Our aim for the project week is to explore various DTI analysis tools developed by NAMIC to perform tractography.

Progress

So far, DTI analysis has been tested on a smaller dataset using various fiber tracking tools. The preprocessing is yet to be implemented and the DTI pipeline has to be tested on a larger dataset.

References

• Casey B. Goodlett, P. Thomas Fletcher, John H. Gilmore, Guido Gerig. Group Analysis of DTI Fiber Tract Statistics with Application to Neurodevelopment. NeuroImage 45 (1) Supp. 1, 2009. p. S133-S142.