2010 Summer Project Week Left ventricular scar segmentation

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  Projects List

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  Scatter plot of the original FA data through the genu of the corpus callosum of a normal brain.

• LVscarFusion.jpg

  Magnetic resonance late gadolinium enhancement images compared with voltage maps of the heart using electrophysiology, and a representation of the MR scar pattern.

Key Investigators

• Beth Israel Deaconess Medical Center: Dana C. Peters, Felix Liu

Objective

We wish to represent the MR scar images in 3D to compare with voltage maps. This will lead to interpretation of the relationship between EP findings and scar.

Approach, Plan

Our approach includes segmentation of the scar, representation, registration with voltage maps, and quantitative evaluation.

Progress

None so far.

Delivery Mechanism

This work will be delivered to the NA-MIC Kit as a (please select the appropriate options by noting YES against them below)

1. ITK Module
2. Slicer Module
   1. Built-in
   2. Extension -- commandline
   3. Extension -- loadable
3. Other (Please specify)

References

• Wolf T, Gepstein L, Dror U, Hayam G, Shofti R, Zaretzky A, Uretzky G, Oron U, Ben-Haim SA. Detailed endocardial mapping accurately predicts the transmural extent of myocardial infarction. J Am Coll Cardiol 2001; 37:1590-1597.
• Desjardins B, Crawford T, Good E, Oral H, Chugh A, Pelosi F, Morady F, Bogun F. Infarct architecture and characteristics on delayed enhanced magnetic resonance imaging and electroanatomic mapping in patients with postinfarction ventricular arrhythmia. Heart Rhythm 2009; 6:644-651.
• Bogun FM, Desjardins B, Good E, Gupta S, Crawford T, Oral H, Ebinger M, Pelosi F, Chugh A, Jongnarangsin K, Morady F. Delayed-enhanced magnetic resonance imaging in nonischemic cardiomyopathy: utility for identifying the ventricular arrhythmia substrate. J Am Coll Cardiol 2009; 53:1138-1145