2011 Summer Project Week long shape regression
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Longitudinal Shape Regression - Huntington's Disease
Key Investigators
- Utah: James Fishbaugh, Marcel Prastawa, Guido Gerig
- Iowa: Hans Johnson
Objective
To begin processing longitudinal Huntington's disease data and to apply our shape regression framework to available data. We are interested in the evolution of sub-cortical structures in the brain.
We would like to estimate continuous growth scenarios for several shapes of interest, which can eventually be combined with a framework for 4D registration or 4D atlas construction, to statistically analyze the growth variability within a population.
Approach, Plan
- Segment sub-cortical structures
- Estimate growth trajectories
References
Fishbaugh, J., Durrleman, S., Gerig, G. "Estimation of Smooth Growth Trajectories With Controlled Acceleration From Time Series Shape Data". MICCAI 2011. To appear.