Projects:RegistrationLibrary:RegLib C42
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v3.6.1
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Contents
v3.6.1
Slicer Registration Library Case #42:
Intra-subject Brain MRI: serial assessment of brain development in autism
Input
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fixed image/target | moving image |
Modules
Slicer 3.6.3 recommended modules:
Objective / Background
This is a typical case of change assessment.
Keywords
MRI, brain, head, intra-subject, T1, tumor, change assessment, pediatric MRI
Input Data
- reference/fixed : T1 SPGR , 1x1x1 mm voxel size, 256x256x192 ,sagittal
- moving: T1 SPGR , 1x1x1 mm voxel size, 256x256x192 ,sagittal
Overall Strategy
- run rigid/affine registration (BRAINSfit) without initialization (initial positions are sufficiently close)
- run 5x5x5 nonrigid regista=ration (BRAINSfit BSpline) using the above affine as input
Procedures
- Phase I: Register Rigid/Affine
- open Registration : BrainsFit module (presets: BRAINSfit_Xf1 or _Xf2
- Input Parameters:
- Fixed: "Autism_T1_2yrs"
- Moving: "Autism_T1_4yrs"
- Registration Phases:
- select/check Include Rigid registration phase , Include Scale Versor 3D , Include Affine, Include BSpline
- Output Settings
- select a new "Slicer BSpline Transform", rename to "Xf3_Affine+BSpline" or similar "
- select a new volume "Output Image Volume, rename to "Autism_T1_4yrs_Xf3", indicating that this is the result volume after being resampled with the Xf3 transform.
- Output Image Pixel Type: check "ushort". As a general rule, match the datatype of the input image, unless specific reason demands otherwise (e.g. you wish to avoid rounding of interpolation effects). The "float" datatype is 4-bytes per pixel and can produce unnecessary large files.
- Registration Parameters:
- increase Number Of Samples to 300,000
- Registration Parameters: set Number Of Grid Subdivisions to 5,5,5
- Leave all other settings at default
- click Apply
- Input Parameters:
Registration Results
original unregistered | |
affine registered | nonrigid registered (5,5,5 BSpline unmasked) |
visualization of the nonrigid deformation component only |
Download
- Data
- Presets