Projects:RegistrationLibrary:RegLib C12

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Slicer Registration Use Case Exampe #12: Liver Tumor Cryoablation

this is the fixed reference image. All images are aligned into this space lleft this is the moving image. The transform is calculated by matching this to the reference image this is the moving image. The transform is calculated by matching this to the reference image LEGEND

lleft this indicates the reference image that is fixed and does not move. All other images are aligned into this space and resolution
lleft this indicates the moving image that determines the registration transform.

lleft intra-op MRI lleft pre-op CT lleft pre-op CT+contrast
0.78 x 0.78 x 2.5 mm
512 x 512 x 96
RAS
0.95 x 0.95 x 5 mm
512 x 512 x 41
RAS
0.95 x 0.95 x 5 mm
512 x 512 x 42
RAS

Objective / Background

We seek to align the pre-operative CT with the intra-operative MRI.

Keywords

MRI, CT, IGT, intra-operative, liver, cryoablation, change detection, non-rigid registration

Input Data

  • Button red fixed white.jpgreference/fixed : intra-op MRI, 0.78 x 0.78 x 2.5 mm axial, RAS orientation.
  • Button green moving white.jpg moving: pr-op CT, 0.95 x 0.95 x 5 mm voxel size, axial, RAS orientation.

Methods

Registration Results

[

Download

Link to User Guide: How to Load/Save Registration Parameter Presets


Discussion: Registration Challenges

  • large differences in FOV
  • strong differences in image contrast between MRI & CT
  • contrast enhancement and pathology and treatment changes cause additional differences in image content
  • we have strongly anisotropic voxel sizes with much less through-plane resolution

Discussion: Key Strategies