2008 Summer Project Week:DWIRegistrationOMT

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OMT Deformation Grid on MRI

OMT Deformation Grid on DWI

Key Investigators

• Allen Tannenbaum, Tauseef ur Rehman, John Melonakos (Georgia Tech)
• Marek Kubicki, Sylvain Bouix (BWH)

Objective

• To explore the portability of Optimal Mass Transport (OMT) Non-rigid Registration code to the NAMIC toolkit.
• To determine applicability of OMT registration algorithm for DWI Distortion Correction.

Approach, Plan

• Conversations with Core 2 to analyze the project
• Discussions with Core 3 to see how to adapt the existing code for DWI Registration
• Make a project plan

Progress

• Currently the algorithm and registration framework is available in MATLAB
• Preliminary results with DWI baseline image correction.
• DWI and MRI image intensity normalization using CSF and White-Matter/Grey-Matter segmentations performed to make sure both image volumes are on same footing so that Mass Transport mapping is found without introducing structural distortions.
• Further experiments required to fine tune the normalization step.
• Slicer command line module created for interfacing with OMT Registration algorithm. A few issues with nrrd files being resolved.
• Discussions with Core 2 on existing infrastructure within ITK for non-rigid registration and re-use of demons diffeomorphic registration filter framework for OMT Registration filter.

References

• Optimal Mass Transport Registration Project Page