2008 Winter Project Week:Cortical Thickness

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Key Investigators

  • UNC: Heather Cody Hazlett, Martin Styner, Clement Vachet
  • GE: Jim Miller

Objective

We would like to create an end-to-end application within Slicer3 allowing individual and group analysis of regional and local cortical thickness.

Such a workflow applied to the young brain (2-4 years old) is our goal in order to start a longitudinal study of early brain development in autism.

See our Roadmap for more details.

Approach, Plan

Our plan during this week is to use several Slicer3 modules, and apply them on our pediatric data.

We would like to apply EMSegment to segment our pediatric data using our own atlas and compare it whith a segmentation tool (itkEMS) developped in our lab.

Progress

Attended:

  • EMSegment breakout session
  • Registration breakout session

We have learnt how to use the new EMSegment module.

EMSegment was run successfully on the tutorial template-data.

EMSegment was run successfully on our own data (T1-weigthed and T2-weighted) using our pediatric atlas.

We have started a reliability study comparing EMSegment and itkEMS, using ten scans of the same patient.