2009 Summer Project Week Cardiac Blood Pool Registration
Patient 1
Patient 2
Intensity average of 16 patients registered to each other
Key Investigators
- MIT: Michal Depa, Polina Golland
- BWH: Ron Kikinis, Ehud Schmidt
Objective
We would like to register cardiac MRA images with the objective of using atlas-based methods to segment the left atrium.
This segmentation could then be used as an input to an automated cardiac ablation scar segmentation algorithm.
Approach, Plan
There are numerous registration algorithms available and it is unclear which one is the best for cardiac blood pool registration. We would like to experiment with different ones and see which one can provide the best results.
Progress
Although we haven't had the opportunity to compare as many algorithms as we would have liked, we obtained what at first sight seem like very good results using a combination of Slicer's affine registration and a log-domain diffeomorphic demons deformable registration.
We are now planning to further investigate these results and also try to improve them using different algorithms, especially in the second deformable registration stage.
References
- Dru F., Vercauteren T., An ITK Implementation of the Symmetric Log-Domain Diffeomorphic Demons Algorithm, The Insight Journal, January - June 2009.
