2010 Winter Project Week CardiacAblationScarSeg
- MIT: Michal Depa, Polina Golland
- BWH: Ron Kikinis, Ehud Schmidt
Atrial fibrillation, which means irregular contractions of the heart’s atria, is one of the most common heart conditions and can have very serious consequences such as stroke and heart failure. A technique called catheter radio-frequency (RF) ablation has recently emerged as a treatment for this condition. It involves burning the cardiac tissue that is responsible for the fibrillation. Even though this technique has been shown to work fairly well on atrial fibrillation patients, repeat procedures are often needed to fully correct the condition because surgeons lack the necessary tools to quickly evaluate the success of the procedure.
The objective of this project is to automatically segment the scar created by RF ablation in delayed enhancement MR images acquired after the procedure. We would then be able to present the surgeon with a visualization showing the size, shape and location of the scar.
Our earlier work focused on segmenting the left atrium (LA), the heart chamber on which RF ablations are usually done, in blood pool MR images. We used a label fusion segmentation algorithm which consisted of first registering all of the training images to the test one and then
Given corresponding cardiac blood pool and post-procedure delayed enhancement images for each patient, our plan is to first segment the LA in the blood pool image, then transfer this segmentation to the delayed enhancement image of the same patient. We then intend to use this prior information to search for the ablation scar using intensity-based algorithms. This prior knowledge of the LA location will allow us to avoid most false positives.
I have only done some very preliminary experiments.