2012 Winter Project Week:GeometricMetamorphosisTBI

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  Projects List

Key Investigators

• Kitware: Danielle Pace, Stephen Aylward
• UNC: Marc Niethammer
• Utah: Marcel Prastawa
• UCLA: Andrei Irimia, Jack van Horn

Objective

• Image registration of longitudinal neuroimaging data of traumatic brain injury (TBI), with the aim of predicting long term outcome and designing treatment plans.
• The geometric metamorphosis registration algorithm jointly estimates global background deformations and local pathology changes. This allows injury changes to be analysed without the impact of background motion.

Approach, Plan

• Continue validation studies in simulated and actual image data.
• Meet together to discuss next steps.

Progress

• Project discussions between Danielle, Stephen and Jack.
• Data discussions between Danielle and Marcel.
• Group discussion on TBI project identified requests from algorithm developers to DBP and clarified clinical realities.

Delivery Mechanism

This work will be delivered to the NA-MIC Kit as a Slicer extension.

References

Marc Niethammer, Gabriel L. Hart, Danielle F. Pace, Paul M. Vespa, Andrei Irimia, John D. Van Horn, and Stephen R. Aylward, Geometric Metamorphosis, MICCAI 2011.