Apr 2005 - Oct 2005 Milestones

Reproducibility of T1-based multi-spectral data & derived morphometry

• Reproducibility evaluation of MR signal and full segmentations as function of B0, B1, unwarping (A. Dale)
• Unwarping code for all human BIRN sites (J. Jovicich)
• Protocol/correction recommendations for multiple platforms (A. Dale)

Reproducibility of T2-based multi-spectral data & derived morphometry

• Complete test retest multi-spectral acquisitions (1.5T/3T) at Duke (J. MacFall)
• Complete multi-spectral GM/WM/CSF segmentations (unwarping) (J. MacFall)
• Protocol recommendation related to specific applications (J. MacFall)

Reproducibility of diffusion MR images and derived data: FA and ADC

• Acquisition & analysis of test-retest DTI (1.5T, 4T, TE, b effects) (S. Mori)
• Protocol/correction recommendations that includes # averages, TE, b-value, number/directions of encoding gradients, MRI platforms (S. Mori, A. Song, L. Frank)