Project Week 25/Slice-to-Volume Registration to Support MRI guided Interventions

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Key Investigators

• Gino Gulamhussene (University of Magdeburg, Germany)
• Andras Lasso (Queen's University, Canada)

Project Description

Objective	Approach and Plan	Progress and Next Steps
The objective of this project is to drive the discussion under which circumstances medical image registration can be used to support MRI guided liver interventions. Furthermore a simple implementation of a state of the art method to register iMRI to MRI shall show the principle possibility of such an approach.	discuss the applicability of Slice-to-Volume registration of intra-interventional MRI to pre-interventional MRI to support liver interventions. (insights from radiologists would be valuable) give an overview of factors that determin the applicability of (StV) registration to support liver interventions in MRI implement state of the art algorithm to register orthogonal iMRI slices to MRI volume	Progress discussed the motivation for non-regit registration of planing MRI/CT to iMRI/iCT reducing the need of contrast agend administration in both iMRI and iCT providing any additional information that is either containt in planning data or added / annotated in its reference frame providing additional information from other modalities like PET (Pre-fusing several planing volumes) reducing mental effort for interventionalist I got showed a manual workflow in Slicer to solve the basic task with state of the art methods I got insights into the development with and for Slicer I started to implement a python Slicer Extension to automate the previously found workflow using several aspects of slicer (CLI, Python Scripting, simpleITK, sitkUtils) Next Steps finishing the Slicer extension implementing a way to generate ground truth (simulated respiration deformation in iMRI) implementing the evaluation tools (visual inspection and computed metrics)

Illustrations

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  non-regid transformation result

Background and References

• 2011_Winter_Project_Week:Intra-ProceduralProstateMotion