Projects:RegistrationLibrary:RegLib C15

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Slicer Registration Librar Case 15: Brain MR Alignment along AC-PC line

			LEGEND this indicates the reference data that determines the transform. this indicates the moving image that is being realigned.
Fiducials		T1 SPGR
2 points marking AC-PC line 3+ points marking midline		1 mm isotropic 256 x 256 x 116 RAS

Keywords

MRI, brain, head, anterior commissure, posterior commissure, AC-PC Line, Talairach, fiducial alignment

Input Data

• moving: T1 MPRAGE 1x1x1 mm voxel size

Registration Challenges

• A dedicated module for AC-PC alignment is used.
• the only difficulty lies with accurate placement of the AC-PC fiducials. Depending on image resolution and contrast these can be difficult to find.
• midline fiducials should be easily obtainable from axial and coronal views. 3 midline fiducials suffice; more is recommended for a more robust solution.

Key Strategies

• this is a special case of fiducial-based alignment. Instead of aligning two sets of fiducial pairs, only one set of fiducials is aligned with a predefined orientation: The plane defined by the midline fiducials is aligned to be vertical in coronal/axial views, and the line defined by the AC-PC line is rotated to be horizontal in a sagittal view.

Registration Results

Download

• Data
  • Registration Library Case 15: Brain alignment along AC-PC Line (Data,Presets, Solution, zip file 21 MB)
• Presets
  • Registration Library Case 15: Presets for AC-PC module (.mrml file 172 kB)
  • Link to User Guide: How to Load/Save Registration Parameter Presets
• Documentation
  • Registration Library Case 15: step-by step tutorial (PowerPoint file 3.2 MB)