CTSC:ACRIN 09/30/09
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The objectives of the workshop are:
- to enhance interpretation of DICOM images through the use of 3D visualization and analysis
- to gain experience with interactive, quantitative assessment of complex anatomical structures and functional images
- to present current directions of quantitative imaging as a biomarker in clinical trials
Upon completion of this course, participants should be able to
- Describe the methods used for basic analysis of quantitative imaging parameters
- Describe the principles of image registration, segmentation, and volume measurement, and select and use appropriate software for 3D reconstruction
- Identify key analysis and acquisition requirements for multi-center quantitative studies
- Evaluate the impact of quantitative analysis methodology on their research interest
Workshop outline
- 30 min (Dr Kasia Macura, Johns Hopkins): Overview of imaging biomarkers and their use in clinical trials
- 30 min (Dr Randy Gollub, Harvard MGH): Generic principles of image registration, segmentation, visualization (technical aspects)
- 30 min (Dr Jeff Yap, Harvard DFCI): Description and case studies of each of the imaging biomarkers and requirements for standardized acquisition in multi-center trials (e.g. RSNA QIBA)
- DCE-MRI (pre/post-therapy breast tumor perfusion)
- volumetric CT (e.g. lung tumor segmentation and volumetric measurement)
- FDG-PET/CT (pre/post-therapy whole-body imaging with SUV quantification)
Slides
Presentations are posted on the CTSA IWG website and wiki.
